Background: Primary Hyperoxaluria Type 1 (PH1) is an inborn error of metabolism caused by mutations in the AGXT gene, which encodes for the hepatocyte-specific enzyme alanine: glyoxylate aminotransferase (AGT).AGT catalyzes the conversion of glyoxylate to glycine in the peroxisome and prevents the build-up of oxalate which occurs in PH1.This causes
Immunological memory and tolerance represent major achievements and advantages of adaptive immunity.Organisms bearing adaptive immunity display prominent competitive advantages in the fight against infections.Memory immune cells are preserved for decades and are able to repel a second attack Splash Guards of an infectious agent.However, studies per
As it has several features that optimize information 5-HTP processing, it has been proposed that criticality governs the dynamics of nervous system activity.Indications of such dynamics have been reported for a variety of in vitro and in vivo recordings, ranging from in vitro slice electrophysiology to human functional magnetic resonance imaging.Ho
In recent years, a surge of interest in biodiversity conservation have led to the development of new approaches to facilitate ecologically-based conservation policies and management plans.In particular, image classification and predictive distribution modeling applied to forest habitats, constitute a crucial issue as forests constitute the most wid